Sarris Lab

Microbiology and Host-Microbe Interactions Lab at IMBB FORTH & Dept. of Biology, UoC

Selected Publications

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All Publications

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  1. Marchetti, A., Orlando, M., Digiovanni, S., Christakis, C., Tsopanakis, V., Arapitsas, N., Pavlidis, I. V., Sarris, P., Mangiagalli, M., & Lotti, M. (2025). Xylan degradation in the halotolerant bacterium bacillus altitudinis relies on glycosidic hydrolases from families 11 and 30. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/acs.jafc.5c06247 doi: 10.1021/acs.jafc.5c06247.
  2. Xiaohui Liu, Peihong Wang, Sai Wang, Weixue Liao, Mingyan Ouyang, Sisi Lin, Rongpeng Lin, Panagiotis F Sarris, Vasiliki Michalopoulou, Xurui Feng, Zinan Zhang, Zhengyin Xu, Gongyou Chen, Bo Zhu, The circular RNA circANK suppresses rice resistance to bacterial blight by inhibiting microRNA398b-mediated defense, The Plant Cell, 2025;, koaf082, https://doi.org/10.1093/plcell/koaf082
  3. Tsakiri, D., Kotsaridis, K., Michalopoulou, V.A., Zhang, N., Marinos, S., Kountourakis, N., Kokkinidis, M., Martin, G.B., Sarris, P.F., Subcellular targets and recognition mechanism of Ralstonia solanacearum effector RipE1, ISCIENCE (2025), doi: https://doi.org/10.1016/j.isci.2025.11230.
  4. Chalmoukis, C., Droubogiannis, S., Michalopoulou, V.A., Triga, A., Sarris, P.F., Katharios, P., 2025. Development and characterization of fluorescent protein-tagged vibrio harveyi strains as a versatile tool for studying infection dynamics and strain interactions. Pathogens 14. https://doi.org/10.3390/pathogens14030247
  5. Chen, R., Chen, K., Yao, X., Zhang, X., Yang, Y., Su, X., Lyu, M., Wang, Q., Zhang, G., Wang, M., Li, Y., Duan, L., Xie, T., Li, H., Yang, Y., Zhang, H., Guo, Y., Jia, G., Ge, X., . . . Sun, D. (2024). Genomic analyses reveal the step- wise domestication and genetic mechanism of curd biogenesis in cauliflower. Nature Genetics, 56(6), 1235–1244. https://doi.org/10.1038/s41588-024-01744-4
  6. Liu, C., Mentzelopoulou, A., Hatzianestis, I. H., Tzagkarakis, E., Skaltso- giannis, V., Ma, X., Michalopoulou, V. A., Romero-Campero, F. J., Romero- Losada, A. B., Sarris, P. F., Marhavy, P., B ̈olter, B., Kanterakis, A., Gutierrez- Beltran, E., & Moschou, P. N. (2024). A proxitome-rna-capture approach reveals that processing bodies repress coregulated hub genes. The Plant Cell, 36(3), 559–584. https://doi.org/10.1093/plcell/koad288
  7. Wu, Y., Wang, S., Wang, P., Nie, W., Ahmad, I., Sarris, P. F., Chen, G., & Zhu, B. (2024). Suppression of host plant defense by bacterial small rnas packaged in outer membrane vesicles. Plant Communications, 5(4). https://doi.org/10.1016/j.xplc.2024.100817
  8. Kotsaridis, K., Michalopoulou, V. A., Tsakiri, D., Kotsifaki, D., Kefala, A., Kountourakis, N., Celie, P. H. N., Kokkinidis, M., & Sarris, P. F. (2023). The functional and structural characterization of xanthomonas campestris pv. campestris core effector xopp revealed a new kinase activity. The Plant Journal, 116(1), 100–111. https://doi.org/10.1111/tpj.16362
  9. Kotsaridis, K., Tsakiri, D., & Sarris, P. F. (2023). Understanding enemy’s weapons to an effective prevention: Common virulence effects across micro- bial phytopathogens kingdoms. Critical Reviews in Microbiology, 49 (4), 528– 542. https://doi.org/10.1080/1040841X.2022.2083939
  10. Mermigka, G., Michalopoulou, V. A., Amartolou, A., Mentzelopoulou, A., Astropekaki, N., & Sarris, P. F. (2023). Assassination tango: An nlr/nlr-id immune receptors pair of rapeseed co-operates inside the nucleus to activate cell death. The Plant Journal, 113(6), 1211–1222. https://doi.org/10.1111/tpj.16105
  11. Marchal, C., Michalopoulou, V. A., Zou, Z., Cevik, V., & Sarris, P. F. (2022). Show me your id: Nlr immune receptors with integrated domains in plants. Essays in Biochemistry, 66(5), 527–539. https://doi.org/10.1042/EBC20210084
  12. Michalopoulou, V. A., Mermigka, G., Kotsaridis, K., Mentzelopoulou, A., Celie, P. H. N., Moschou, P. N., Jones, J. D. G., & Sarris, P. F. (2022). The host exocyst complex is targeted by a conserved bacterial type-iii effector that promotes virulence. The Plant Cell, 34(9), 3400–3424. https://doi.org/10.1093/plcell/koac162
  13. Sertedakis, M., Kotsaridis, K., Tsakiri, D., Mermigka, G., Dominguez-Ferreras, A., Ntoukakis, V., & Sarris, P. F. (2022). Expression of putative effectors of different xylella fastidiosa strains triggers cell death-like responses in various nicotiana model plants. Molecular Plant Pathology, 23(1), 148–156.
    https://doi.org/10.1111/mpp.13147
  14. Christakis, C. A., Daskalogiannis, G., Chatzaki, A., Markakis, E. A., Mermigka, G., Sagia, A., Rizzo, G. F., Catara, V., Lagkouvardos, I., Studholme, D. J., & Sarris, P. F. (2021). Endophytic bacterial isolates from halophytes demonstrate phytopathogen biocontrol and plant growth promotion under high salinity. Frontiers in Microbiology, 12. https://doi.org/10.3389/fmicb.2021.681567
  15. Andersen, E. J., Nepal, M. P., Purintun, J. M., Nelson, D., Mermigka, G., & Sarris, P. F. (2020). Wheat disease resistance genes and their diversification through integrated domain fusions. Frontiers in Genetics, 11. https://doi.org/10.3389/fgene.2020.00898
  16. Catara, V., Suming, D., & Sarris, P. F. (2020). Molecular mechanisms for resistance to biotic stresses. In A. Gentile, S. La Malfa, & Z. Deng (Eds.), The citrus genome (pp. 281–294). Springer International Publishing. https://doi.org/10.1007/978-3-030-15308-3_16
  17. Kioukis, A., Michalopoulou, V. A., Briers, L., Pirintsos, S., Studholme, D. J., Pavlidis, P., & Sarris, P. F. (2020). Intraspecific diversification of the crop wild relative brassica cretica lam. using demographic model selection. BMC Genomics, 21(1), 48. https://doi.org/10.1186/s12864-019-6439-x
  18. Mermigka, G., Amprazi, M., Mentzelopoulou, A., Amartolou, A., & Sarris, P. F. (2020). Plant and animal innate immunity complexes: Fighting different enemies with similar weapons. Trends in Plant Science, 25(1), 80–91. https: //doi.org/10.1016/j.tplants.2019.09.008
  19. Mermigka, G., & Sarris, P. F. (2019). The rise of plant resistosomes. Trends in Immunology, 40(8), 670–673. https://doi.org/10.1016/j.it.2019.05.008
  20. Paschalidis, K., Tsaniklidis, G., Wang, B.-Q., Delis, C., Trantas, E., Loulakakis, K., Makky, M., Sarris, P. F., Ververidis, F., & Liu, J.-H. (2019). The inter- play among polyamines and nitrogen in plant stress responses. Plants, 8(9). https://doi.org/10.3390/plants8090315
  21. Licciardello, G., Caruso, A., Bella, P., Gheleri, R., Strano, C. P., Anzalone, A., Trantas, E. A., Sarris, P. F., Almeida, N. F., & Catara, V. (2018). The luxr regulators pcor and rfia co-regulate antimicrobial peptide and alginate production in pseudomonas corrugata. Frontiers in Microbiology, 9. https://doi.org/10.3389/fmicb.2018.00521
  22. Ma, Y., Guo, H., Hu, L., Martinez, P. P., Moschou, P. N., Cevik, V., Ding, P., Duxbury, Z., Sarris, P. F., & Jones, J. D. G. (2018). Distinct modes of derepression of an arabidopsis immune receptor complex by two different bacterial effectors. Proceedings of the National Academy of Sciences, 115 (41), 10218–10227. https://doi.org/10.1073/pnas.1811858115
  23. Mathioudakis, M. M., Khechmar, S., Owen, C. A., Medina, V., Ben Mansour, K., Tomaszewska, W., Spanos, T., Sarris, P. F., & Livieratos, I. C. (2018). A thioredoxin domain-containing protein interacts with pepino mosaic virus triple gene block protein 1. International Journal of Molecular Sciences, 19(12). https://doi.org/10.3390/ijms19123747
  24. Michalopoulou, V. A., Vicente, J. G., Studholme, D. J., & Sarris, P. F. (2018). Draft genome sequences of pathotype strains for three pathovars belonging to three xanthomonas species. Microbiology Resource Announcements, 7 (12), 10.1128/mra.00923–18. https://doi.org/10.1128/mra.00923-18
  25. Huh, S. U., Cevik, V., Ding, P., Duxbury, Z., Ma, Y., Tomlinson, L., Sarris, P. F., & Jones, J. D. G. (2017). Protein-protein interactions in the rps4/rrs1 immune receptor complex. PLOS Pathogens, 13(5), e1006376–. https://doi.org/10.1371/journal.ppat.1006376
  26. Trantas, E. A., Mpalantinaki, E., Pagoulatou, M., Markakis, E., Sarris, P. F., Ververidis, F., & Goumas, D. E. (2017). First report of bacterial apical necro- sis of mango caused by pseudomonas syringae pv. syringae in greece. Plant Disease, 101 (8), 1541–1541. https://doi.org/10.1094/PDIS-04-17-0498-PDN
  27. Duxbury, Z., Ma, Y., Furzer, O. J., Huh, S. U., Cevik, V., Jones, J. D. G., & Sarris, P. F. (2016). Pathogen perception by nlrs in plants and animals: Parallel worlds. BioEssays, 38 (8), 769–781. https://doi.org/10.1002/bies.201600046
  28. Sarris, P. F., Cevik, V., Dagdas, G., Jones, J. D. G., & Krasileva, K. V. (2016). Comparative analysis of plant immune receptor architectures uncov- ers host proteins likely targeted by pathogens. BMC Biology, 14 (1), 8. https://doi.org/10.1186/s12915-016-0228-7
  29. Trantas, E. A., Sarris, P. F., Mpalantinaki, E., Papadimitriou, M., Ververidis, F., & Goumas, D. E. (2016). First report of xanthomonas hortorum pv. hederae causing bacterial leaf spot on ivy in greece. Plant Disease, 100(10), 2158. https://doi.org/10.1094/PDIS-03-16-0312-PDN
  30. Sarris, P. F., Duxbury, Z., Huh, S. U., Ma, Y., Segonzac, C., Sklenar, J., Derbyshire, P., Cevik, V., Rallapalli, G., Saucet, S. B., Wirthmueller, L., Menke, F. L. H., Sohn, K. H., & Jones, J. D. G. (2015). A plant immune receptor detects pathogen effectors that target wrky transcription factors. Cell, 161(5), 1089–1100. https://doi.org/10.1016/j.cell.2015.04.024
  31. Sarris, P. F., & Jones, J. D. G. (2015). Plant immune receptors mimic pathogen virulence targets. Oncotarget, 6(19), 16824–16825. https://doi.org/10.18632/oncotarget.4838
  32. Saucet, S. B., Ma, Y., Sarris, P. F., Furzer, O. J., Sohn, K. H., & Jones, J. D. G. (2015). Two linked pairs of arabidopsis tnl resistance genes independently confer recognition of bacterial effector avrrps4. Nature Communi- cations, 6(1), 6338. https://doi.org/10.1038/ncomms7338
  33. Trantas, E. A., Sarris, P. F., Pentari, M. G., Mpalantinaki, E. E., Ververidis, F. N., & Goumas, D. E. (2015). Diversity among seudomonas corrugata and seudomonas mediterranea isolated from tomato and pepper showing symptoms of pith necrosis in greece. Plant Pathology, 64 (2), 307–318. https://doi.org/10.1111/ppa.12261
  34. Trantas, E. A., Licciardello, G., Almeida, N. F., Witek, K., Strano, C. P., Duxbury, Z., Ververidis, F., Goumas, D. E., Jones, J. D., Guttman, D. S., Catara, V., & Sarris, P. F. (2015). Comparative genomic analysis of multiple strains of two unusual plant pathogens: Pseudomonas corrugata and pseudomonas mediterranea. Frontiers in Microbiology, 6. https://doi.org/10.3389/fmicb.2015.00811
  35. Licciardello, G., Bella, P., Devescovi, G., Strano, C. P., Sarris, P. F., Catara, A. F., Venturi, V., & Catara, V. (2014). Draft genome sequence of pseudomonas mediterranea strain cfbp 5447, a producer of filmable medium-chain-length polyhydroxyalkanoates. Genome Announcements, 2 (6), https://doi.org/10.1128/genomea.01260-14
  36. Sarris, P. F., Ladoukakis, E. D., Panopoulos, N. J., & Scoulica, E. V. (2014). A phage tail-derived element with wide distribution among both prokaryotic domains: A comparative genomic and phylogenetic study. Genome Biology and Evolution, 6(7), 1739–1747. https://doi.org/10.1093/gbe/evu136
  37. Sohn, K. H., Segonzac, C., Rallapalli, G., Sarris, P. F., Woo, J. Y., Williams, S. J., Newman, T. E., Paek, K. H., Kobe, B., & Jones, J. D. G. (2014). The nuclear immune receptor rps4 is required for rrs1slh1-dependent constitutive defense activation in arabidopsis thaliana. PLOS Genetics, 10 (10), e1004655–. https://doi.org/10.1371/journal.pgen.1004655
  38. Williams, S. J., Sohn, K. H., Wan, L., Bernoux, M., Sarris, P. F., Segonzac, C., Ve, T., Ma, Y., Saucet, S. B., Ericsson, D. J., Casey, L. W., Lonhienne, T., Winzor, D. J., Zhang, X., Coerdt, A., Parker, J. E., Dodds, P. N., Kobe, B., & Jones, J. D. G. (2014). Structural basis for assembly and function of a heterodimeric plant immune receptor. Science, 344(6181), 299–303. https://doi.org/10.1126/science.1247357
  39. Sarris, P. F., Trantas, E. A., Baltrus, D. A., Bull, C. T., Wechter, W. P., Yan, S., Ververidis, F., Almeida, N. F., Jones, C. D., Dangl, J. L., Panopoulos, N. J., Vinatzer, B. A., & Goumas, D. E. (2013). Comparative genomics of multiple strains of pseudomonas cannabina pv. alisalensis, a potential model pathogen of both monocots and dicots. PLOS ONE, 8(3), e59366–. https://doi.org/10.1371/journal.pone.0059366
  40. Trantas, E. A., Sarris, P. F., Mpalantinaki, E. E., Pentari, M. G., Ververidis, F. N., & Goumas, D. E. (2013). A new genomovar of pseudomonas cichorii, a causal agent of tomato pith necrosis. European Journal of Plant Pathology, 137(3), 477–493. https://doi.org/10.1007/s10658-013-0258-8
  41. Gazi, A. D., Sarris, P. F., Fadouloglou, V. E., Charova, S. N., Mathioudakis, N., Panopoulos, N. J., & Kokkinidis, M. (2012). Phylogenetic analysis of a gene cluster encoding an additional, rhizobial-like type iii secretion system that is narrowly distributed among pseudomonas syringae strains. BMC Microbiology, 12(1), 188. https://doi.org/10.1186/1471-2180-12-188
  42. Sarris, P. F., Trantas, E. A., Mpalantinaki, E., Ververidis, F. N., Gouma, S. E., & Goumas, D. E. (2012). First report of pseudomonas viridiflava caus- ing a bacterial blight of artichoke bract leaves. Plant Disease, 96(8), 1223– 1223. https://doi.org/10.1094/PDIS-12-11-1084-PDN
  43. Sarris, P. F., Trantas, E. A., Mpalantinaki, E., Ververidis, F., & Goumas, D. E. (2012). Pseudomonas viridiflava, a multi host plant pathogen with significant genetic variation at the molecular level. PLOS ONE, 7 (4), e36090–. https://doi.org/10.1371/journal.pone.0036090
  44. Sarris, P. F., Gao, S., Karademiris, K., Jin, H., Kalantidis, K., & Panopoulos, N. J. (2011). Phytobacterial type iii effectors hopx1, hopab1 and hopf2 enhance sense-post-transcriptional gene silencing independently of plant r gene-effector recognition. Molecular Plant-Microbe Interactions®, 24 (8), 907–917. https://doi.org/10.1094/MPMI-01-11-0010
  45. Sarris, P. F., & Scoulica, E. V. (2011). Pseudomonas entomophila and pseu- domonas mendocina: Potential models for studying the bacterial type vi secretion system. Infection, Genetics and Evolution, 11(6), 1352–1360. https://doi.org/10.1016/j.meegid.2011.04.029
  46. Sarris, P. F., Zoumadakis, C., Panopoulos, N. J., & Scoulica, E. V. (2011). Distribution of the putative type vi secretion system core genes in klebsiella spp. Infection, Genetics and Evolution, 11(1), 157–166. https://doi.org/10.1016/j.meegid.2010.09.006
  47. Sarris, P. F., Skandalis, N., Kokkinidis, M., & Panopoulos, N. J. (2010). In silico analysis reveals multiple putative type vi secretion systems and effector proteins in pseudomonas syringae pathovars. Molecular Plant Pathology, 11(6), 795–804. https://doi.org/10.1111/j.1364-3703.2010.00644.x
  48. Tampakaki, A. P., Skandalis, N., Gazi, A. D., Bastaki, M. N., Panagiotis F., S., Charova, S. N., Kokkinidis, M., & Panopoulos, N. J. (2010). Playing the “harp”: Evolution of our understanding of hrp/hrc genes1. Annual Review of Phytopathology, 48(Volume 48, 2010), 347–370. https://doi.org/10.1146/annurev-phyto-073009-114407
  49. Moschou, P. N., Sarris, P. F., Skandalis, N., Andriopoulou, A. H., Paschalidis, K. A., Panopoulos, N. J., & Roubelakis-Angelakis, K. A. (2009). Engineered polyamine catabolism preinduces tolerance of tobacco to bacteria and oomycetes. Plant Physiology, 149(4), 1970–1981. https://doi.org/10.1104/pp.108.134932
  50. Sarris, P., Abdelhalim, M., Kitner, M., Skandalis, N., Panopoulos, N., Doulis, A., & Lebeda, A. (2009). Molecular polymorphisms between populations of pseudoperonospora cubensis from greece and the czech republic and the phy- topathological and phylogenetic implications. Plant Pathology, 58(5), 933– 943. https://doi.org/10.1111/j.1365-3059.2009.02093.x